Smart Wrinkle Cream
Smart Wrinkle Cream
Hygieia Smart Wrinkle Cream is a comprehensive anti-aging system. It leverages Bio Active Idebenone for high-grade protection and the Liposomal Delivery System for optimal penetration, ensuring that every application is a step toward truly visible, lasting skin renewal.
A Truly Smart Cream
The Hygieia Smart Wrinkle Cream is a product of intelligent design, engineered using Artificial Intelligence (AI) to optimize the challenging process of dermal penetration. This technology was specifically employed to fine-tune the formulation's Liposomal Delivery System, ensuring the delicate Phospholipids correctly encapsulate the active ingredients and achieve the perfect structure for seamless fusion with skin cell membranes. The result is a scientifically-validated delivery mechanism that guarantees maximum absorption and superior efficacy of the wrinkle-fighting compounds deep within the skin's surface.
Tanya
After 3 weeks of daily application as directed- big change noted. Money well spent.
Linda
Obviously, I had hoped it would work faster but I can say it is working and the change is visible in only a month, much better than any other crepey skin creams I have tried
Sherry
The cream is great. My arms feel tighter and my neck looks more firm. My skin looks more plump and healthy, I really like it.
Barbara
I’m seeing results after one and one half jars used
Jill
Very good cream that feels nice on my skin. It feels more hydrated and firm after 3 weeks of use.
Bio Active Idebenone – The Advanced Defense System
Bio Active Idebenone – The Advanced Defense System
At the heart of the Smart Wrinkle Cream lies 1% Bio Active Idebenone, a compound revered in advanced cosmeceuticals for its unparalleled antioxidant potential.
Idebenone: Surpassing Traditional Antioxidants
Idebenone is a synthetic analog of Coenzyme Q10 (CoQ10), a fundamental substance found in every cell that is critical for energy production. While CoQ10 is an effective antioxidant, Idebenone has been structurally modified to enhance its stability, potency, and permeability.
- Superior Antioxidant Cascade: Independent scientific ratings have placed Idebenone at the top of the scale for protection against oxidative stress, often outperforming widely used antioxidants like Vitamin C, Vitamin E, Alpha Lipoic Acid, and even CoQ10 itself. It functions by neutralizing free radicals across multiple cellular compartments, providing a comprehensive defense against environmental damage.
- Mitochondrial Protection: Idebenone's structure allows it to interact effectively within the mitochondria, the cell's powerhouses. By protecting the mitochondrial membrane from oxidative damage, it helps cells maintain optimal energy levels required for essential functions like repair, renewal, and collagen synthesis—processes that naturally slow down with age.
The Meaning of "Bio Active"
In the highly reactive environment of skincare formulation, an ingredient's activity—its capacity to work as intended—can be fleeting. The term Bio Active is a promise of quality and stability:
- Guaranteed Potency: The formulation process is rigorously controlled to prevent the Idebenone from degrading due to exposure to light, heat, or incompatible chemical interactions within the cream base. This ensures that the compound remains in its most effective state when it is applied to the skin.
- Optimal Bioavailability: "Bio Active" signifies that the Idebenone is prepared in a state that the skin's cellular structures can readily recognize, absorb, and utilize. This maximizes the therapeutic window, allowing the compound to exert its full wrinkle-reducing and protective effects.
The 1% concentration of this Bio Active compound provides a clinical-grade defense against photoaging, making it a powerful cornerstone in the daily fight against deep wrinkles and fine lines.
The SMART Liposomal Delivery System
The SMART Liposomal Delivery System
A cream containing the world's best ingredients is ineffective if those ingredients cannot reach their biological targets. The skin's stratum corneum (outer layer) is an incredibly efficient barrier designed to keep pathogens out and moisture in. This barrier equally resists the penetration of large, active cosmetic molecules.
The Hygieia Smart Wrinkle Cream overcomes this challenge through its Liposomal Delivery System, a sophisticated method of transportation that is the defining characteristic of the "smart" technology. This system is enabled by the inclusion of Phospholipids in the formulation.
The Mechanism of Liposome Technology
Phospholipids are fatty molecules that are the fundamental building blocks of human cell membranes. When processed under specific conditions, these phospholipids spontaneously form microscopic, spherical vesicles called liposomes.
- Encapsulation and Protection: Liposomes act as microscopic shields, encapsulating the vulnerable active ingredients, such as Retinol and Idebenone. This encapsulation protects them from surface degradation (e.g., oxidation from air or surface enzymes) before they are absorbed.
- Targeted Penetration (Biomimicry): Because the liposomal membrane is structurally identical to the skin's cell membrane, the liposome is naturally recognized as "self." This biomimetic recognition allows the liposomes to seamlessly fuse with the skin cells, depositing their potent cargo deep within the skin layers. This dramatically increases the bioavailability and efficacy of the actives compared to standard creams, where actives often remain superficially on the skin's surface.
- Sustained Release: The liposomal structure allows for a slower, controlled release of the actives into the skin over several hours. This is crucial for maximizing the ingredient's benefits and is particularly beneficial for Retinol, as it helps to minimize the risk of irritation, redness, or sensitivity often associated with immediate high-dose delivery.
This delivery system ensures that the most powerful ingredients—the 1% Bio Active Idebenone and Retinol—are not wasted on the surface but are driven precisely to the areas where cellular repair and renewal are needed, justifying the claim of intelligent delivery.
The Supporting Cast: Synergy for Comprehensive Renewal
The Supporting Cast: Synergy for Comprehensive Renewal
The "smart" formulation extends beyond the two pillars to include essential synergistic ingredients that complement the primary wrinkle fighters:
- Retinol (as Vitamin A): Included for its proven role in cell communication. Retinol encourages faster cell turnover, exfoliates at a cellular level, and signals the deeper layers of the dermis to increase collagen and elastin production. This action directly addresses the fine lines and wrinkles resulting from sun damage and natural aging. Its stability and potency are enhanced exponentially by the Liposomal Delivery System.
- Sodium Hyaluronate (Hyaluronic Acid): This is the salt form of Hyaluronic Acid, valued for its smaller molecular size, which allows it to penetrate deeper into the skin. As a powerful humectant, it draws and binds vast amounts of moisture to the skin, instantly plumping the epidermis. This effect visibly diminishes the depth of fine lines and restores a supple, youthful smoothness to the skin's surface.
- Jojoba Oil: An incredibly stable, non-comedogenic oil that closely mimics human sebum. It works as an excellent emollient to reinforce the compromised skin barrier, reducing moisture loss (TEWL) and creating a protective, non-greasy cushion that supports the skin's elasticity.
- Alpha Lipoic Acid: A secondary, yet potent, antioxidant that is both water- and fat-soluble, allowing it to provide broader protection across different layers of the skin.
60 Day Money Back Guarantee
60 Day Money Back Guarantee
We know you’ll love our creams as much as we do. In fact, if for any reason you’re not completely satisfied, just return them, even empty, within 60 days of your first order, and we’ll issue a full refund.What should you expect in 60 days?
Liposomal Skincare 🇺🇸
This cream uses cutting edge Liposomal technology to penetrate deep and deliver effective ingredients.
It's All In The Liposomes
Deep Absorption– Delivers active ingredients deep into the skin, rather than just sitting on the surface.

