Advanced Crepey Skin Repair

About 6 weeks with daily use on one area, such as your arms — or roughly a month if you're treating arms and chest together. That's why most customers choose the 3-jar option: it covers a full course of daily use at the best per-jar price, and consistent daily use is what produces the results in our reviews.

The formula is fragrance-free, paraben-free and sulfate-free, and the liposomal delivery is designed to reduce irritation compared with unencapsulated actives. If your skin is very sensitive, patch-test on your inner forearm for a day or two first. The cream does contain Retinol and Glycolic Acid, so if you're using prescription skin treatments or have a skin condition, check with your doctor or pharmacist — and as with any retinol product, daytime SPF is recommended.

From the link in any of your order emails — no phone calls, no hoops, no questions. You can skip a month, pause, or cancel anytime, and it takes effect immediately. Subscribing just locks in the 20% price for as long as you want deliveries.

Then you're covered. Use it daily for up to 60 days, and if you don't see smoother, firmer-looking skin, email us for a refund — even if the jar is empty. We can offer that because most women who use it daily don't send it back.

Idebenone is a bio-engineered version of Coenzyme Q10 (CoQ10), a substance naturally present in almost every cell in your body, where it helps produce energy and protect the cell. Because Idebenone is modeled after a substance your skin already recognizes, it can integrate into your skin's own protective pathways. When your skin faces UV, pollution, or other stressors, it creates free radicals that damage cells and degrade collagen. Idebenone's role is to hunt down these free radicals and neutralize them on contact — before they can break down the collagen that keeps skin looking smooth.

Liposomes are tiny spherical vesicles with a lipid bilayer — the same material as your skin's own cell membranes. They encapsulate active ingredients and carry them deep into the skin, improving delivery and stability while boosting hydration (by restoring the skin's barrier) and reducing irritation. Because they're biocompatible, they're readily accepted by the skin and suitable for a wide range of skin types.

Apply cream to wet skin up to twice daily, rubbing into the desired area thoroughly for about a minute. Allow another minute to absorb before applying other products. For added benefit, mist with purified water. Best used with a daily SPF cream for UVA/UVB protection.

Idebenone — a water-soluble CoQ10 analog and mitochondrial antioxidant. Squalane — a naturally occurring lipid that keeps skin soft and supple. Hyaluronic Acid — a strong water-attractant that helps skin hold moisture. Retinol (Vitamin A) — stimulates cell turnover and collagen and elastin production. Glycolic Acid — turns on skin-renewal genes and gently exfoliates so other actives penetrate. Vitamin E — a fat-soluble antioxidant that strengthens the barrier. Collagen — the structural protein behind youthful, elastic skin. L-Lysine, L-Ornithine and L-Glutamine — amino acids that cross-link and switch on collagen genes to support repair.

Many women notice smoother, firmer skin after just one application, but the most significant and lasting results come from daily, consistent use. Many customers report visibly younger, smoother skin within 21 days. A 3-month or 6-month supply is ideal for sustained benefits.

In a published study, participants applied 1.0% idebenone twice daily over six weeks and saw a 26% reduction in skin roughness and dryness, a 37% increase in hydration, a 29% decrease in fine lines and wrinkles, and a 33% overall improvement in photodamage. Immunofluorescence indicated decreases in pro-inflammatory cytokines (IL-1β, IL-6) and MMP-1, along with an increase in collagen I. (McDaniel 2005; PubMed 17129261.)