Skin Care
Why is Artichoke Extract Good For Your Health?
You may have had artichoke dip, but what about artichoke extract? Although it’s often considered a vegetable, the artichoke is actually a type of thistle that has been used for centuries because of its potential medicinal benefits. It has been shown to possibly lower blood sugar levels and improve digestion, heart health, and liver health. Here are some of the top benefits of artichoke extract that might have you reaching for it next time you’re in the supplement aisle. Plenty of Nutrients Artichokes are full of tons of powerful nutrients. Even a medium artichoke has 6.9 grams of fiber, 4.2 grams of protein, and only 0.2 grams of fat! Being low in fat and rich in fiber, vitamins, minerals, and antioxidants, especially folate and vitamins C and K makes it a great choice when you’re looking to start a healthy diet. It also supplies important minerals magnesium, phosphorus, potassium, and iron. Plus, a medium artichoke is only about 60 calories, so it’s a great addition to your plant-based diet. Don’t forget that it’s one of the most antioxidant-rich vegetables out there. May Improve Cholesterol A review of over 700 people found that “supplementing with artichoke leaf extract daily for 5-13 weeks led to a reduction in total and “bad” LDL cholesterol.” In another study of 143 adults with high cholesterol, artichoke leaf extract was taken daily for six weeks. They found that there was an 18.5% and 22.9% decrease in the total cholesterol and LDL cholesterol. Other studies in animals showed decreased triglycerides after regular consumption of artichoke extract. It may even boost the “good” cholesterol, or HDL cholesterol in those adults with high cholesterol. It’s thought that this positive impact on cholesterol happens due to the presence of luteolin. Luteolin is an antioxidant that actually prevents cholesterol formation. Artichoke leaf extract also encourages the body to process cholesterol more efficiently, leading to overall lower levels. Regulating Blood Pressure For those with high blood pressure, artichoke leaf extract may be an effective supplement in controlling it. A study of 98 men with high blood pressure found that 12 weeks of daily artichoke extract intake reduced diastolic and systolic blood pressure on average 2.76 and 2.85 mmHg. It’s not yet totally clear why artichoke extract can have these results. One though is that it contains an enzyme that can help to widen the blood vessels. Another thought is that it stems from the levels of potassium, another natural way to help regulate blood pressure. Liver Health Another benefit that may come from consuming artichoke leaf extract is the positive impact on your liver. Some studies show that taking artichoke leaf extract can help to protect your liver from damage and promote the growth of new tissue. It can also help to increase the production of bile, which functions to remove harmful toxins in your liver. One trial of 90 people with non-alcoholic fatty liver disease showed that 600 mg of artichoke extract taken daily for two months resulted in improved liver function. These positive results have been seen in other studies, as well. It’s thought that this may be from the antioxidants cynarin and silymarin in the artichoke. Improve Digestive Health Thanks to the high fiber content of artichoke, taking the extract of artichoke leaf can help to promote friendly gut bacteria, reduce the risk of some bowel cancers, and alleviate constipation and diarrhea. It also contains insulin which can act as a prebiotic. One study of the impact of artichoke extract on the digestive tract even showed it can also provide relief from bloating, nausea, and heartburn. The antioxidant cynarin may once again be the cause of these positive results. It’s believe that it promotes the production of bile, accelerates gut movement, and improves the digestion of certain fats. Helping Symptoms of Irritable Bowel Disease Luckily for those who suffer from the digestive system condition IBS, artichoke leaf extract may be a supplement that can help with symptoms. A study in people with IBS who consumed artichoke leaf extract daily for six weeks, 96% of the participants stated that the extract was at least as effective as other IBS treatments, like antidiarrheals and laxatives, to ease symptoms. Another study of 208 IBS sufferers showed an approximate 26% reduction in symptoms and overall improvement of their quality of life by 20%. This may be from the anti-spasmodic properties of artichoke extract, meaning it can help with the stomach muscle spasms that are common in IBS. It can also help to balance gut bacteria and reduce inflammation. Lowering Blood Sugar An exciting benefit of artichoke extract is the effect it has on blood sugar. In a study of 39 overweight adults, those who consumed kidney bean and artichoke extract daily for two months showed a lowered fasting blood sugar level. This result isn’t fully explained yet, though it may be in part thanks to artichoke extract slowing down the activity of alpha-glucosidase. This enzyme breaks down starch into glucose and could potentially impact a person’s blood sugar level. May Have an Anticancer Effect Some studies have shown that artichoke extract has impaired cancer growth. There are some antioxidants that may be responsible for this, namely ruin, quercetin, silymarin, and gallic acid. One study in test tubes and animals found that silymarin could help to prevent and treat skin cancer. Currently, there are no human studies about the effects of artichoke leaf extract on cancer prevention or treatment. However, the current studies provide some hope. Whatever your reason for taking artichoke leaf extract, there are some significant benefits for your overall wellness. Always consult with a physician before starting a new supplement.
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Surprising Benefits of Hyaluronic Acid
The body produces a number of natural, beneficial substances that aid in both internal and external health. Hyaluronic acid, a polysaccharide, is just one of those substances. Also known as hyaluronan, hyaluronic acid is found in the eyes, skin, and joints in large amounts. The top function of hyaluronic acid is in lubricating the eyes and keeping them moist, yet it has a number of other surprising uses. Compounds of hyaluronic acid are synthesized and used as a dietary supplement, as well as to prevent health issues caused by aging. Hyaluronic acid doesn’t just come as a supplement, however. It is also found in eye drops, serums, and injections, in order to provide amazing benefits. Taking hyaluronan can aid users in a number of incredible ways, including: Healthy skin First and foremost, hyaluronic acid helps the skin, making it healthier and supple. This is because the body contains over half of its hyaluronic acid in the skin, which decreases over time due to aging and exposure to certain elements. When you take hyaluronic acid supplements, you are replenishing the substance in your skin, which has diminished. This hydration of the skin makes it healthier, minimizes wrinkles, and decreases skin conditions such as dermatitis. Osteoarthritis and joint pain Since hyaluronic acid is also found in the joints and works as an aid for keeping the space between bones and joints lubricated, as it diminishes it stops working as effectively. This can cause pain from bones rubbing against each other and is detrimental for those with osteoarthritis. Users of hyaluronic acid are adding the essential substance back into the body, allowing the joints to be lubricated again. They tend to experience a decrease in pain when taking supplements or injections. Aids in wound healing Hyaluronic acid is a key to fast wound healing. It works by regulating levels of inflammation and telling the body to add more blood vessels to damaged or wounded areas. When applied directly to skin wounds, hyaluronic acid decreases pain and shrinks their size. Replete with antibacterial properties, it can also reduce the risk of infection. Helps with acid reflux Studies have begun to show that hyaluronic acid may have a positive effect on sufferers of acid reflux. Acid reflux damages the esophagus and causes pain. Using hyaluronic acid can actually help the damaged esophagus to heal. Those with regular acid reflux will likely experience life-changing benefits from the use of hyaluronic acid. Eye lubrication and moisture Dry eyes are very common and the problem tends to get worse with age. Hyaluronic acid works great as a treatment for the issue because it is used for retaining moisture. Using eye drops will help to decrease your itchy, dry eyes by lubricating and moisturizing for a time. Bladder assistance Bladder pain, abdominal pain, and the need to urinate are all signs that you could have an issue with your bladder. Hyaluronic acid can be a helpful remedy, relieving pain, as well as the desire to urinate often.
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What's You Largest Organ? Your Skin! Read Some Interesting Facts
Your organs perform the most vital functions of keeping your body alive. They pump blood, filter it, regulate hormones, and more. An organ doesn’t have to be large to be important, but it’s always interesting to know what the largest organs are. Medically speaking, an organ is a cluster of tissue with a specific purpose. This structure is opposed to muscle, bone, tendon, or some other composition of cells that may or may not do only one thing. According to many experts, there are 79 organs in the human body. But some estimate that there are more. The skin is currently the largest known organ. But there is a contender that may prove to be the largest with more research. It is called the interstitium. The Largest Organ Is the Skin More research is needed on the interstitium, so for now the largest organ is the skin. This amazing organ covers the entire body. It comprises about 16 percent of the body mass. The skin has several purposes. It regulates your body temperature. It protects your body from the environment and germs. It stores water, vitamin D, and fat. It processes sensory input. Skin Facts There are over 3,000 skin disorders. The skin has three layers: the dermis, the epidermis, and the hypodermis. These stacked layers hold water, sweat glands, body fat, nerves, oil glands, hair follicles, and more. The skin’s functions are many, and they include protecting us from damaging UV rays. The skin has interesting interactions with other organs. You can see from the facts below that skin function can be impacted by many other organs, but it also impacts the other organs because it regulates so much fluid and processes sunlight. Where Does Skin Color Come From? Skin color is created with melanin. People with darker skin have both more and deeper-colored melanin particles than fairer people. Original humans had darker skin, whereas fair skin is an adaptation to mostly northern climates. Fairer skin allows people to absorb more UV, helping them to process more vitamin D. The interstitium The interstitium hasn’t been studied much compared to other organs. The body of research that put it on the map as a possible organ was completed in 2018. This mass holds nearly 93 percent of your body fluid. It is a series of spaces in the body filled with fluid. The spaces are made of flexible connective tissue, but you’d be right in assuming that everyone may not agree that this constitutes an organ. Being mostly space, the interstitium is nevertheless very important tissue. Much of it resides under the skin, but some of it is attached to the body’s connective tissue. It is also found around the arteries and veins and in the linings of your lungs, digestive tract, and urinary system. The Liver The liver is the largest solid organ inside the body. It is approximately the size of a football and weighs between three and three-and-a-half pounds. The liver has several important functions. It produces bile. It detoxifies the blood. It makes blood proteins. It turns sugars into glycogen. It helps clot the blood properly. The liver holds about a pint of blood at a time. The Brain The brain is the second largest internal organ after the liver in almost all humans. The brain weighs about three pounds also. It is generally about 5.5 inches by 6.5 inches by 3.6 inches. The brain does very important things for the body, including regulating thoughts and feelings. It processes information, controls behavior, and interprets the physical sensations people have.
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Your skin gets a lot of attention. Whether good or bad, it’s one of the first things people see about you.
While everyone wants to look like they’ve got the skin of a model, our skin condition can be so far from this reality that we start to lose confidence. Perfect skin may be unrealistic for many, but a healthy glow is achievable for nearly everyone. Hygieia Skin products are a vital component of many people’s complexion. These products have raving customers because they truly produce results. No one can stop time and keep their skin from aging. But products from Hygieia come amazingly close. These creams are full of vitamins and antioxidants that promote collagen production in even the most fragile areas like the eyes and neck. Skin quality improves dramatically with the use of firming products from Hygieia. However, there are other things people can do to improve their complexion and skin firmness. In combination with Hygieia products, water, exercise, sleep, and an antioxidant-rich diet will keep your skin looking years younger. Self-confidence is an issue for so many women. Our skin quality can affirm our sense of value or harm it. Here are some ways skin quality can create a more confident you. A Great First Impression Put simply, your skin is one of the first things people notice about you. If you have trouble making a great first impression, it’s time to take a look at your skin quality. Your skin makes a first impression for good reason. It can give telltale clues about the health of your internal organs, your lifestyle, and whether you are well-rested and energetic. In a perfect world, people wouldn’t judge us based on our looks alone. But the truth is that skin offers important information about people. Skin conditions can come from any combination of factors, including genetics. But the way we tackle our problems is also something people want to know about us. Even if our skin isn’t naturally flawless or we’ve had skin conditions in the past, what we are doing now to look good matters. Glowing skin tells people that you are energetic, joyful, and healthy. If you have or have had skin problems for any reason, products from Hygieia will help improve your appearance. They won’t correct a lack of sleep or an unhealthy diet, but they will help provide essential vitamins and antioxidants. Social Confidence Having skin that appears youthful and is actually healthier from added vitamins and antioxidants can boost your confidence because of improved social interactions. People always want to see a glowing, smiling face when they interact with others. But when you feel nervous about your skin, your social interaction isn’t always at its best. Creating great situations is a lot easier with a little help from added vitamins, antioxidants, and collagen production. Beauty Every woman cares about feeling beautiful. It’s engrained in us to look amazing whenever we can. And people who look beautiful tend to have an easier time making friends and working with others. Of course, beauty isn’t a guarantee that your social aspirations will magically come true. And beauty is more than skin deep, as they say. But you can always bring out your natural beauty with science-based products that create collagen and truly add nutrients to your skin. Healthy From the Inside Out Healthy skin is a real achievement. It’s not very often that people actually have perfect skin, or even the best skin they can have. We just don’t eat perfectly and sleep enough. We get stressed. We have allergies. The list goes on. But you can promote skin health by using products that don’t just add a superficial glow. Hygieia products truly grow collagen and add essential compounds to your skin. Doing the right thing for your skin is part of growing your confidence by taking care of your health. A healthy diet, enough rest, and tons of water are essential for great-looking skin. And many of us work hard to give our skin these things. But we aren’t perfect. You can fill in your skin’s nutritional, water, and vitamin gaps with products that contain essential ingredients. Making up these necessary factors will keep your skin healthy even when you aren’t perfect about lifestyle factors. Putting Your Best Foot Forward Using the right products in combination with lifestyle choices that promote healthy skin are all part of putting your best foot forward socially. With enough rest, the right collagen-promoting products, excellent food, and exercise, you will get as close to perfect skin as it gets.
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Defining and Treating Crepey Skin
We all love to have glowing, smooth skin. But with time, that’s not always what we get! If you know you haven’t got the glow you want, you may be trying to define what type of skin you have so you can treat it. Defining Crepey Skin Crepey skin is thin, first and foremost. It has the same appearance as crepe paper that has been crunched a few times. It is most common in larger areas, such as under the eyes or around the upper inner arms. What Causes Crepey Skin? While sun damage is the most common cause of crepey skin, it is not the only way to get this type of skin. It can also come from aging, not enough moisture, and weight loss. Any combination of these factors can also cause crepey skin. Pollution, stress, and smoking can cause extra aging of the skin, contributing to crepey skin. The oil in your skin also dramatically reduces with age, which can cause it to go crepey. You can tell if lack of moisture is the cause of your crepey skin by noticing if it comes and goes with hydration or very hot weather. If it does, your crepey skin is caused by lack of moisture. Preventing Crepey Skin The absolute most important thing to do to prevent crepey skin is to stay out of the sun as much as you can, wear sunscreen, and use protective clothing. The second most important thing you can do is to moisturize with body lotion. Products with glycerin or hyaluronic acid are the best for preventing and improving the appearance of crepey skin. Helpful oils include coconut oil, olive oil, and cocoa butter. There are no known specific foods for preventing crepey skin, but antioxidant-rich foods improve the skin overall. Eat colorful fruits and veggies to get these antioxidants. Foods high in Vitamin C are also beneficial, since this vitamin promotes collagen production. These aren’t overnight fixes, but they make a long-term difference in the deterioration of your skin. You have to be consistent with them. How To Treat Crepey Skin There are several treatments for crepey skin. They include: Idebenone Cream This skin-firming cream with Retinol & Hyaluronic Acid treats your crepey skin using science. It contains vitamins and antioxidants that will help prevent aging over time. It helps to eliminate free radicals and promote rejuvenation. Fraxel Fraxel, or fractional laser treatment, treats the skin by heating it up with lasers. This encourages collagen growth and smooths skin from underneath. It is especially good for treating skin under the eyes. Ultrasound This also heats up the skin and smooths it from underneath. This treatment requires topical anaesthetics, so it is used only on the face and neck. Cryolipolysis This treatment removes small areas of fat. It dissolves the fat cells by freezing the lipids, so it’s non-invasive. This works mostly on areas with excess fat. Fillers These compounds work by promoting collagen. There are a lot of different kinds that can all be injected with a syringe. Over the Counter Skin with a lot of sun damage can improve with the use of products containing retinoids, alpha-hydroxy acids, or peptides. They can help regenerate cells.
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Idebenone & Facial Rejuvenation
You might know about the effects of the sun on the skin. In general, more exposure to the sun increases the visible aging of the skin. Most people who are worried about premature aging are diligent about sunscreen. It’s the best method for making sure that you don’t age the skin too quickly. Over time, aging will naturally occur no matter what you do. There’s no way to completely age-proof your skin. But you can visibly improve the appearance of wrinkles by treating the skin with antioxidants. Hygiea Skin has created new products to introduce these antioxidants to the skin along with vitamins, amino acids, minerals, and other beneficial compounds. For example, it’s known that vitamin E is a powerful way to promote skin rejuvenation. The new products from Hygiea Skin have been found to be much more effective than straight vitamin E. It is also known that some other essential vitamins for preventing aging cannot be applied topically or even through supplements. They have to be eaten to have a strong effect on the skin. Of course, Idebenone products cannot bypass science and help your body to absorb vitamins through the skin that must be ingested. But Hygiea Skin has created an incredible patented formula that introduces an exceptional amount of vitamins, minerals, and antioxidants to the skin. These are effective and safe to use topically. Hygiea Skin has created their creams with the help of science as they seek to defy the aging process using the knowledge available to the scientific community. In one study, Idebenone was injected into the fat underneath the skin along with hyaluronic acid over a period of two months. The study also included another mixture of hyaluronic acid, vitamins, amino acids, minerals, coenzymes, and antioxidant substances. Both groups of injections produced significant results in the improved appearance of wrinkles and skin firmness. Whether you’re young and want to work on your wrinkles before they become exaggerated or you’re older and your skin is showing its age, Idebenone has scientifically proven results for you! The basic concept of Idebenone products is that they are more effective than vitamin E or CoQ10. These products use proven formulas to introduce nutrients and antioxidants to the skin. The products are formulated at different strengths for different needs. Two percent and four percent solutions are the standard options. What would you do if you could go back in time and do something for your skin? You’d probably wear more sunscreen. You’d probably eat more antioxidant-rich foods like berries and leafy greens. Probably everyone would drink more water, eat less sugar, and take up an anti-aging regime with the right products. The next best thing to treating your skin like this is to introduce more antioxidants to it at whatever stage of life you are in. Antioxidants are a safe and healthy addition to your beauty routine. They can be applied topically with the right creams. They absorb deep into the skin. It’s almost as if you had eaten your blueberries in the first place! You can’t quite go back in time to firm your skin up. But creams with Idebenone are the next best thing. The principle behind these products is that they are healthy and minimally invasive. Many people are tempted to undergo surgery or injections to visibly tighten their skin. But the effects of these treatments only last so long. The natural beauty of the face is very difficult to preserve when you use these tactics. With a science-based product like Idebenone from Hygiea Skin, you can bring out your skin’s natural beauty without treating it harshly or interrupting your daily routine. These minimally invasive formulas have been tested on both men and women with great results. With the right science and tons of vitamins and minerals, Idebenone brings a healthy glow and visible tightening back to your skin. Forget surgery and go with a treatment that works long-term. The natural beauty and vitality of the skin is visible when you use Idebenone products. You don’t have to continually use them to get results, but you will want to when you notice visible tightening in just eight weeks. No matter what kind of damage the sun and time have done to your skin, you can reverse the results significantly with Idebenone products from Hygiea Skin.
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Idebenone Skin Cream & Photo-damaged Skin - The Results Are In
Have you heard of Idebenone? An antioxidant lower molecular weight analogue of coenzyme Q10, Idebenone evidently is effective in protecting against cell damage that would be caused by oxidative stress. Typically, this stress appears in a variety of methods that are biochemical, in vivo, and cell biological. It is also said to suppress sunburn cell formation that is in living skin. There have been no clinical studies to determine Idebenone’s effectiveness for photodamaged skin in topical skincare formulations. However, a non-vehicle control study was undertaken which evaluated .5% and 1% idebenone commercial formulations for topical safety and efficacy in photodamaged skin. There were 41 females with moderate photodamaged skin between the ages of 30-65 studied. These subjects were randomized to use a blind labelled skincare preparation of either .5% or 1% idebenone twice daily for six weeks. Both came with identical lotion bases. At the baseline, three weeks, and six weeks, they were assessed by a blinded expert grader for fine lines/wrinkles, roughness/dryness, and overall photodamage improvement. At baseline and after six weeks, electrical conductance readings and 35 mm photography were done for skin surface hydration. Not only that, but subjects who were randomly selected, had punch biopsies at baseline and after six weeks. The biopsies were stained using immunofluorescence microscopy for these specific antibodies: interleukin IL-6, interleukin IL-1b, matrix metalloproteinase MMP-1, and collagen I. Results showed that after using the 1% idebenone formula for six weeks, there was a 26% reduction in skin roughness/dryness, a 29% reduction in fine lines/wrinkles, a 37% increase in skin hydration, and a 33% improvement in the overall assessment of photodamaged skin . After six weeks using the .5% idebenone formula, subjects saw a 23% reduction in skin roughness/dryness, a 27% reduction in fine lines/wrinkles, a 37% increase in skin hydration, and a 30% improvement in the overall assessment of photodamaged skin. Results of the randomized immunofluorescence microscopy showed a decrease in IL-1b, IL-6, and MMP-1 and an increase in collagen I for both concentrations.
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Idebenone and Anti-Aging Skincare, a Match Made in Heaven
Idebenone is a biochemical molecule nearly identical to the well-known coenzyme Q10. The importance of coenzyme Q10 in improving heart failure rates, reducing free radical wear and tear on the cells, and slowing down certain kinds of neurological damage has been long known. While coenzyme Q10 is a natural compound present in all aerobic organisms, idebenone is a synthetic molecule that is apparently a lot more potent than its nature-made cousin. It was created by a pharmaceutical company in Japan with the view of using it in the treatment of Alzheimer’s disease. The effects of idebenone on Alzheimer’s were limited, but as it turned out, this molecule might have other uses. In particular, skincare companies are looking into idebenone due to its powerful antioxidant properties. Essentially, it fights free radicals, which makes it such a promising component in skincare products. Idebenone is more water-soluble than coenzyme Q10 and slightly different from it in its cellular structure and antioxidant activity. Because of this, idebenone is more effective than coenzyme Q10 when it comes to neutralizing certain types of free radicals. In particular, idebenone does a better job than coenzyme Q10 in protecting skin cells from damage caused by impaired blood flow. The effects of idebenone on skin Idebenone has been used as a pharmaceutical agent for decades, but has only recently arrived on the skincare scene. The parallels between coenzyme Q10 and idebenone are extended to this field as well. A few studies have shown coenzyme Q10 to be helpful in reducing wrinkles, but the samples were relatively small and the results inconclusive. It only made sense, therefore, to apply the same research to idebenone, the newer, synthetic analog to coenzyme Q10. The results, so far, are very promising. Research has shown that idebenone offers effective protection to the skin against antioxidative stress and works to reverse the damage caused by long-term exposure to harmful UV rays. In particular, it has the ability to suppress sunburn cell formation in the skin. Usage of idebenone-containing skincare products has been found to reduce skin roughness and dryness, improve skin hydration, reduce pigment spots, and diminish fine lines and wrinkles. It also led to an increase of collagen – a vital component that makes the skin look firmer and younger. All of this makes idebenone a highly promising active ingredient in the treatment of aging, sun-damaged skin. While the chemical structure of idebenone is very similar to that of coenzyme Q10, it appears that in practical application, its anti-aging effects on the skin are a lot more pronounced. Is an idebenone cream worth trying? There are several established anti-free-radical agents currently in use in the skincare products market, including vitamin C derivatives, retinoids and, of course, coenzyme Q10. If you have tried some of those and are not happy with the effects, you might achieve better results with an idebenone cream. While more research is definitely needed to establish the effectiveness of idebenone in anti-aging treatment, it appears to be a promising, and some would even say potentially revolutionary skincare compound. Are there any side effects? Generally, using idebenone-containing skin creams is considered safe. The compound has been in clinical use since the 1980s with no recorded adverse effects. Like coenzyme Q10, idebenone is sold over the counter as a nutritional supplement, and idebenone skin creams are apparently risk-free as well. Some individuals, however, have reported undesirable side effects such as irritation, redness, and stinging. When considering the application of idebenone cream, it’s important to keep in mind your previous history with beauty products. If you have experienced adverse reactions to skin creams before, it would be best to test the cream by applying it to a small area of your skin first. How to use idebenone cream There is currently a number of skin creams on the market using idebenone as their main active ingredient. These products can get pricey, so it’s important to learn to maximize their effectiveness. Before applying any idebenone-containing skin cream, open your pores by a steam treatment for ten to fifteen minutes. This will allow the cream to penetrate your skin deeper, giving you more effective results. At the end of the steaming, gently pat your skin dry. Don’t rub your face while drying, as this might cause irritation. Apply the cream to clean, dry skin, focusing on the problematic areas. Like other creams containing antioxidants, idebenone creams must be stored away from direct sunlight, since exposure to UV rays may make the active ingredient less effective. We currently offer 2 Idebenone creams, our Crepe Repair Cream contains .1313% Liposomal Idebenone, and our Mitochondrial Rejuvenator contains 1% Liposomal Idebenone (its very strong).
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